Cannabinoid Hyperemesis Syndrome CHS: Symptoms, Causes, & More

Understanding the underlying genetic cause is crucial for managing the condition and providing appropriate care. If you or a loved one has been diagnosed with Chediak-Higashi Syndrome, it’s important to work closely with healthcare providers to develop a comprehensive treatment plan. The diagnosis is established in a proband with giant inclusions within leukocytes on peripheral blood smear and/or by the identification of biallelic pathogenic variants in LYST on molecular genetic testing. Cedars-Sinai Medical Center, the hospital system that serves West Hollywood and much of the Westside, has been sounding the alarm.

Cannabinoid Hyperemesis Syndrome (CHS)

Melanosomes produce and distribute a pigment called melanin, which is the substance that gives skin, hair, and eyes their color. People with Chediak-Higashi syndrome have oculocutaneous albinism because melanin is trapped within the giant melanosomes and is unable to contribute to skin, hair, and eye pigmentation. The CHS chs symptoms recovery phase starts when you stop your marijuana use. When you do this, your symptoms usually start to go away in few days to a few months. Over time, the symptoms will go away completely unless you start to use again.

Addiction Treatment

A healthier future is on the horizon, take the first step toward it by calling today. More research needs to be done about CHS and its causes and treatment. It is hypothesized that pesticides used on cannabis plants may play a role in CHS as well, but that has not been well researched at this time. Death due to CHS is uncommon, but it is important to know that Drug rehabilitation the severity of vomiting that can occur with CHS can lead to serious chemical abnormalities, which can have negative consequences including death. Because this disorder is extremely rare, there is no need to screen relatives unless clinical suspicion is high. Even if a sibling is a carrier, the likelihood of them encountering another carrier and having children is extremely low.

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• However, unless hematopoietic stem cell transplantation is done, most patients with Chédiak-Higashi syndrome die of infections by age 7 years.
• Research shows it hits after years of daily, high-dose use—think multiple times a day for a decade.
• In most cases, the symptoms of the syndrome will disappear pretty fast.
• If you use cannabis often and frequently experience vomiting and nausea, you should tell a healthcare professional.

This process with fatal without treatment and most patients will die by the age of 10 years. Experts also aren’t clear on what causes CHS, or why some people develop it while others don’t. Since it was first identified in 2004 in Australia, researchers have looked at the effects of cannabis on the vomiting centers of the brain. https://ecosoberhouse.com/ Doctors at the hospital ran tests and ordered scans but could not name the source of her unrelenting nausea and vomiting.